- Dairy Farms, Hopkinsville
- Dance Companies, Hopkinsville
- Data Processing Services, Hopkinsville
- Day Spas, Hopkinsville
- Deck, Patio & Gazebo Design, Building, Cleaning, Repair & Maintenance Contractors, Hopkinsville
- Dehumidifying & Ventilating Equipment, Hopkinsville - Suppliers & Wholesalers
- Delicatessen Grocers, Hopkinsville
- Delicatessen Restaurants, Hopkinsville
- Deliverance Church, Hopkinsville
- Dental Bonding & Cosmetic Dentistry, Hopkinsville - Cosmetic Dentist & Tooth Bonding
- Dentists, Hopkinsville
- Department Stores, Hopkinsville
- Developmental Disabilities, Hopkinsville
- Developmentally Disabled Information & Services, Hopkinsville
- Diabetic Equipment & Supplies, Hopkinsville
- Dialysis Clinics, Hopkinsville - Kidney Dialysis Centers
- Diamonds & Precious & Semi-Precious Stones, Hopkinsville
- Dieticians & Diet Counseling, Hopkinsville
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- Direct Mail Advertising Services, Hopkinsville
- Disability And Social Security Attorneys & Lawyers, Hopkinsville
- Disaster Preparedness Equipment & Supplies, Hopkinsville
- Discount Stores, Hopkinsville - Clothing, Grocery, Furniture, Etc
- Distribution Centers, Hopkinsville
- Distribution Services, Hopkinsville
- Diving Instruction, Hopkinsville
- Divorce & Family Law Attorneys & Lawyers, Hopkinsville
- Doctorate Degree, Hopkinsville
- Doctors, Physicians & Surgeons, Hopkinsville
- Donuts, Hopkinsville
- Doors & Door Frames, Hopkinsville - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Drinking Establishments, Hopkinsville
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Hopkinsville
- Dry Cleaning & Laundry, Hopkinsville - Dry Cleaners
- Drywall Contractors, Hopkinsville - Drywall Repair & Installation Services
- Drywall, Insulation & Plaster Contractors, Hopkinsville - Installation & Repair Services
- Durable & Non Durable Goods & Products, Hopkinsville
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