- Machine Shop & Tool Repair Service, Middlesboro
- Machinery Movers & Erectors, Middlesboro
- Machinery, Supplies & Equipment - Business Production Related, Middlesboro
- Machinery, Supplies & Equipment - Business Supplies Related, Middlesboro
- Machinery, Supplies & Equipment - Construction & Contractor Related, Middlesboro
- Major Appliances, Middlesboro - Household & Kitchen
- Malls & Shopping Centers, Middlesboro
- Management Consultants & Services, Middlesboro
- Manicurists & Pedicurists, Middlesboro
- Manufacturing, Middlesboro
- Manufacturing Products, Middlesboro
- Marinas & Marina Services, Middlesboro
- Marriage & Family Counselors, Middlesboro
- Medical Supplies & Equipment, Middlesboro
- Membership Sports & Recreation Clubs, Middlesboro
- Mental Health Clinics, Middlesboro - Treatment Centers
- Mental Health Specialists, Middlesboro - Psychologist, Psychiatrist, Psychotherapist, etc
- Metal Plating & Polishing, Middlesboro
- Metal Repair Service & Blacksmith, Middlesboro - Iron Works
- Methodist Church, Middlesboro
- Mexican Restaurants, Middlesboro
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- Mining, Middlesboro
- Mining Contractors, Middlesboro - Mining Companies, Contractors & Brokers
- Mining Equipment & Supplies, Middlesboro
- Mining Services, Middlesboro
- Mining, Crude-Oil Production, Middlesboro - Mining Companies
- Miscellaneous Commercial & Industrial Supplies & Equipment Rental & Leasing, Middlesboro
- Miscellaneous Government, Middlesboro
- Miscellaneous Photographers, Middlesboro
- Miscellaneous Professional, Middlesboro
- Modular & Mobile Homes For Sale, Middlesboro - Manufactured Homes Sale & Service
- Monuments, Tombstones, Markers & Memorials, Middlesboro
- Mortgage Bankers & Correspondents, Middlesboro
- Motion Picture Pre & Post Production Services, Middlesboro
- Motor Vehicle, Middlesboro
- Motor Vehicle Rental & Leasing, Middlesboro
- Motorcycle Parts, Accessories & Dealers, Middlesboro
- Movie Theaters, Middlesboro
- Moving Companies, Middlesboro
- Moving Truck Rental , Middlesboro
- Muffler Shop & Exhaust Systems, Middlesboro
- Museums, Middlesboro
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